Publications

  1. Yu G, Lyu Y, Jiang L, Jiang L, Wang Y, Yin Y, Zhang J, Yang M, Tang F. ELISA-like QDB method to meet the emerging need of Her2 assessment for breast cancer patients. Front Oncol. 2023;13:920698. doi:10.3389/fonc.2023.920698.
  2. Yu G, Lyu J, Li Y, Zhang Y, Lyu Y, Zhang W, Zhang J, Cai B, Zhang J, Tang F. Validation of absolutely quantitated Ki67 and cyclinD1 protein levels for prognosis of Luminal-like breast cancer patients. Journal of Clinical Laboratory Analysis （2022）, DOI: 10.1002/jcla.24601.
  3. Xin L, Tang F, Song B, Yang M, Zhang J. Objective Quantitation of EGFR Protein Levels using Quantitative Dot Blot Method for the Prognosis of Gastric Cancer Patients. Journal of Gastric Cancer (2021) 21:335–351. doi: 10.5230/jgc.2021.21.e32.
  4. Lyv J, Yu G, Zhang Y, Lyv Y, Zhang W, Zhang J, Tang F. 3D Visualization of the Dynamic Bidirectional Talk Between ER/PR and Her2 Pathways. Technol Cancer Res Treat (2021) 20:15330338211065604. doi: 10.1177/15330338211065603.
  5. Zhang J, Yang M. RE: Assessment of Ki67 in Breast Cancer: Updated Recommendations from the International Ki67 in Breast Cancer Working Group. JNCI: Journal of the National Cancer Institute (2021) 113:1595–1596. doi: 10.1093/jnci/djab093.
  6. Hao J, Zhang W, Lyu Y, Zou J, Zhang Y, Lyu J, Zhang J, Xie S, Zhang C, Zhang J, Tang F. Combined Use of cyclinD1 and Ki67 for Prognosis of Luminal-Like Breast Cancer Patients. Front Oncol (2021) 11:737794. doi: 10.3389/fonc.2021.737794.
  7. Hao J, Lyu Y, Zou J, Zhang Y, Xie S, Jing L, Tang F, Lyu J, Zhang W, Zhang J, Wang X, Chen K, Zhang J. Improving Prognosis of Surrogate Assay for Breast Cancer Patients by Absolute Quantitation of Ki67 Protein Levels Using Quantitative Dot Blot (QDB) Method. Frontiers in Oncology (2021) 11:3673. doi: 10.3389/fonc.2021.737781.
  8. Yu G, Zhang W, Zhang Y, Lv J, Wu S, Sui X, Zhang J, Tang F. Developing a routine lab test for absolute quantification of HER2 in FFPE breast cancer tissues using Quantitative Dot Blot (QDB) method. Sci Rep (2020) 10:12502. doi: 10.1038/s41598-020-69471-4.
  9. Zhu Y, Qi X, Yu C, Yu S, Zhang C, Zhang Y, Liu X, Xu Y, Yang C, Jiang W, Tian G, Li X, Bergquist J, Zhang J. Wang L, Mi J. Identification of prothymosin alpha (PTMA) as a biomarker for esophageal squamous cell carcinoma (ESCC) by label-free quantitative proteomics and Quantitative Dot Blot (QDB). Clin Proteomics (2019) 16:12. doi: 10.1186/s12014-019-9232-6.
  10. Zhang J, Yang M. Developing a growing cancer profile database based on quantitative analysis of protein biomarkers in formalin-fixed paraffin-embedded specimens. Future Oncol (2020) 16:2471–2474. doi: 10.2217/fon-2020-0480.
  11. Zhang W, Yu G, Zhang Y, Tang F, Lv J, Tian G, Zhang Y, Liu J, Mi J, Zhang J. Quantitative Dot Blot (QDB) as a universal platform for absolute quantification of tissue biomarkers. Analytical Biochemistry (2019) 576:42–47. doi: 10.1016/j.ab.2019.04.003.
  12. Qi, X., Zhang, Y., Zhang, Y., Niu, T., Zhang, W., Yang, C., Mi, J., Zhang, J., Tian, T. : High Throughput, Absolute Determination of the Content of a Selected Protein at Tissue Levels Using Quantitative Dot Blot Analysis (QDB). JoVE (Journal of Visualized Experiments) e56885–e56885, 2018.
  13. Tian, G., Tang, F., Yang, Y., Zhang, W., Bergquist, J., Wang, B., Mi, J., Zhang, J. Quantitative dot blot analysis (QDB), a versatile high throughput immunoblot method. Oncotarget 2017 Apr 19. doi:0.18632/oncotarget.17236.

    Patents

    The US

    Jiandi Zhang, Method for diagnosis of cancer based on quantitative biomarkers and a database thereof (US20230049100-A1. 2023, US)

    Jiandi Zhang, Apparatus and method for absolute quantification of biomarkers for solid tumor diagnosis (US-10788484-B2)

    Jiandi Zhang, Apparatus and method for high throughput immunobloting (US-10295544-B2. 2019, US)

    Jiandi Zhang, Multi-unit plate for electroblotting and immunoblot analysis (US-9933418-B2. 2018, US)

    China

    Jiandi Zhang, Method for diagnosis of cancer based on quantitative biomarkers and a database thereof (CN114631027, China)

    Jiandi Zhang，用于实体瘤诊断的生物标志物绝对定量的方法和 装置 (2018800390418 2023，China)

    Jiandi Zhang，一种高通量免疫印迹分析的方法和装置 (2018800051654 2022, China)

    Jiandi Zhang，用于免疫印迹分析的多单元板 (201680029791.8 2019，China)

    Japan

    Jiandi Zhang, Method for diagnosis of cancer based on quantitative biomarkers and a database thereof (JP2022-554301A, Japan)

    Jiandi Zhang，固形腫瘍の診断用のバイオマーカーの絶対定量の方法および装置 (特许第7194128号 2022, Japan)

    Jiandi Zhang，ハイスループットなイムノブロット解析の装置及び方法 (特许7019728 2022, Japan)

    Jiandi Zhang，免疫ブロット分析用マルチユニットプレート (特许第6509366号 2019, Japan)

    Korea

    Jiandi Zhang，높은 처리량 면역 블롯 분석 방법 및 장치 (10-2224922 2021, Korea)

    Singapore

    Jiandi Zhang，APPARATUS AND METHOD FOR ABSOLUTE QUANTIFICATION OF BIOMARKERS FOR SOLID TUMOR DIAGNOSIS (SG11201908865W 2022, Singapore)

    Jiandi Zhang，APPARATUS AND METHOD FOR HIGH THROUGHPUT IMMUNOBLOTING (11201904188R 2021, Singapore)

    Jiandi Zhang ，Multi-unit plate for immunoblot analysis (11201807950T 2019，Singapore)

    The EU

    Jiandi Zhang, Method for diagnosis of cancer based on quantitative biomarkers and a database thereof (EP4052041, EU)

    PCT

    Jiandi Zhang, Method for diagnosis of cancer based on quantitative biomarkers and a database thereof (WO2021087477, PCT)

    Technical note

    1. Zhang, Jessie. Dissection Of QDB Plate and Method Quanticision Diagnotics, Inc. 2020.